Neo40 Professional – NO Booster w/ Methylfolate

Pain Rehab Products, Inc. has partnered with HumanN to offer Neo40 Professional, the only product technology that generates NO gas while improving endogenous NO production. It also comes with a 60 day money back guarantee!

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What is Nitric Oxide (N-O)?

Nitric Oxide is critical in our bodies. Without it, we can’t live. In fact, the loss of Nitric Oxide has been linked to cardiovascular health and has been called the greatest discovery in cardiovascular medicine.


N-O signals our blood vessels to relax, helping to dilate the arteries and increase circulation. It is essential to our very existence. And while it’s abundant in our body’s systems, it’s unstable and depletes, requiring it to be replenished.


Nitric oxide (N-O) is a gas composed of one atom of nitrogen bonded to one atom of oxygen. It serves as a critical signaling molecule in the cardiovascular and circulatory system. That means it affects absolutely every function in our bodies—it’s at the foundational core because without circulation, none of our body’s other systems can work as intended.


Dubbed the “miracle molecule,” the discovery of Nitric Oxide, the first gas to be identified as such, won the Nobel Prize in 1998. This discovery is what N-O Pro is built on.  Pain Rehab Products along with Scientific Health Solutions aspire to bring knowledge and understanding of the importance of N-O to the world.

Nitric Oxide and the body.

Our cardiovascular system relies on Nitric Oxide. So, no matter your age or stage of life, N-O is critical to your health. This is especially poignant when you consider that millions of Americans have blood pressure in the higher range of normal.

This essential molecule signals our blood vessels to relax and expand, creating greater efficiency in the body, greater nutrient delivery, greater oxygenation and so on to every system, organ and tissue in the body. It also supports healthy blood pressure. The point is that N-O is truly linked to everything we do and every breath we take.

If we dive even deeper, we’ll see that Nitric Oxide is tied closely to endothelial function. The endothelium is the tissue that forms a single layer of cells lining our blood vessels and heart.

Growing evidence suggests that promoting optimal endothelial function is associated with increased cardiovascular health. N-O helps keep the endothelium healthy; a healthy endothelium helps produce more N-O. Maintaining the proper functioning of this cycle is important for those who want to achieve their personal best at any age.

Although Nitric Oxide research began in the 1970s, continued advancements have led to a fuller understanding of its impact on:

Supporting healthy blood pressure levels
Promoting cardiovascular and heart health
Dilating arteries for healthy blood flow
Increasing circulation throughout the body
Aiding normal, healthy circulation and arterial function
mobilization of stem and progenitor cells

Why N-O levels drop may surprise you.


We already know our bodies change as we age. This is true for Nitric Oxide levels in the body, as well. By the time we reach 40, studies have shown that we only produce about half or less of the Nitric Oxide we did at age 20. And it continues to decline as we age. There’s also a difference when it comes to gender: by 40, men produce about 50% of the N-O they did in their teens and twenties. And women only produce about 35% of what they did in their twenties at age 50. Yet, our ability to produce and generate N-O within the body is a key element of a healthy body. Which means having an effective strategy to maintain optimal levels is critical because it affects how every cell in our body communicates with each other.


A diet rich in green, leafy vegetables is known to be cardio healthy. For decades nutritionists and scientists thought these effects were from the antioxidants found in those foods. Now we know that it’s due to the dietary nitrates found in green, leafy vegetables and beets. Nitrates are metabolized into Nitric Oxide in the human body by oral nitrate-reducing bacteria. If we don’t consume enough high nitrate vegetables, then we become N-O deficient and our N-O levels begin to fall.

Additionally, people who use antiseptic mouthwash can destroy all the good bacteria in the mouth that are responsible for reducing dietary nitrate into nitrite and Nitric Oxide.  As a result, even though these individuals may eat sufficient amounts of high nitrate vegetables, they may become N-O deficient because they don’t have the right bacteria necessary for metabolizing dietary nitrate.


Physical exercise is the most potent stimulator of Nitric Oxide production and is considered one of the top strategies for supporting overall cardiovascular health.  However, when we don’t exercise, we lose that important signal that tells our body to make more N-O. As a result, the enzyme that makes N-O in response to exercise becomes dysfunctional. This usually leads to N-O insufficiency. Just as in the aging process, the problem is the inability to utilize L-arginine to make Nitric Oxide. The good news, however, is that once we begin to exercise we may regain the functionality of that enzyme and begin to stimulate more N-O production.

Representative Ultrasound before and 10 minutes after NO lozenge

13% increase in vessel diameter causes a 34% increase in blood flow


Average changes in 10 subjects 30 minutes after NO lozenge

Who needs nitric oxide?

Anyone who is aging
Anyone over the age of 40
People with circulation issues
People with low energy
People with sexual dysfunction
Anyone on antacids
Anyone interested in disease prevention
Anyone considering a regenerative medicine procedure

Neo40 Professional Bullet Points

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